The co-relation between low-calorie sweeteners and metabolic syndrome

low-calorie sweeteners

New research study highlights its role of low-calorie sweeteners in triggering the metabolic syndrome. These findings come ahead with the paper presentation held during the Endocrine Society’s annual meeting (Chicago, IL).

What is metabolic syndrome?

  • Scientists refer to metabolic syndrome as an umbrella term.
  • It shadows major health issues such as high blood pressure and sugar levels, high cholesterol and abdominal fats.
  • It is the one associated with doubling the risks of heart disorders.

Management of metabolic syndrome through the medium of yoga:

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The research work marking its presence in the Scandinavian Journal of Medicine & Science in Sports highlights the beneficiary effects of yoga in curbing metabolic syndrome. Here, the researchers are keen on demonstrating the lowering of proinflammatory adipokines with an increase in their anti-inflammatory counterparts.

How do the sweeteners affect our stem and fat cells?

How do the sweeteners effects our stem and fat cells?

This new research comes from George Washington University.

Proceedings of the research study:

The researchers examined the effects of sucralose (a low-calorie sweetener) on the stem cells obtained from human fatty tissues.

These stem cells were then subjected to an obesity-promoting environment mimicked in Petri dishes.

Furthermore, the scientists administered the sucralose solution to the human stem cells. This solution resembled the blood sucralose concentration of those who are regular low-calorie sweetener consumers.

The outcome of this administration was an increase in gene expression related to the production of fats and inflammation.

Parallel examination of the abdominal fat biopsy:

Parallel examination of the abdominal fat biopsy

The above experiment was run in parallel to its counterpart involving abdominal fat biopsy of artificial sweetener consumers.

Outcomes of abdominal fat biopsy study:

  • The study observes that there was no significant increase in the expression of genes in the fat samples incurred from those with a healthy weight.
  • On the other hand, samples from obese participants highlight the overexpression of genes responsible for the production of fat and inflammation.

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According to the researchers, these gene expression patterns further gives rise to metabolic syndrome thereby contributing to pre-diabetes and diabetes.

What does the study finally infers?

What does the study finally infers

On a concluding note, the research finally infers the following:

  • The low-calorie sweeteners are responsible for promoting the accumulation of additional fats within the cells.
  • The entire fat accumulation takes place in a dose-dependent fashion. This dose-dependent fashion indicates that as the regular consumption of artificial sweeteners increases, there is a further increase in fat droplet accumulation.
  • The more the accumulation, the more the individual progresses towards the metabolic syndrome.

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